# gnomAD Production Team at the Broad Institute — Vendor Intelligence Profile
> Source: Vedex (https://vedex.ai) | Generated: 2026-10-05T09:46:38.941Z

## Overview

- **Description**: This dataset was generated using E11.bio's PRISM technology (Protein Reconstruction and Identification through Multiplexing),
a platform that combines viral barcoding, expansion microscopy, and iterative immunolabeling for large-scale neuronal reconstruction.

Neurons in the mouse hippocampal CA3 were transduced with a library of adeno-associated viruses (AAVs)
encoding diverse “protein bits”—small epitope tags that act as combinatorial barcodes. 
Tissue was then processed with an expansion microscopy protocol, physically enlarging the sample ~5×
to achieve an effective voxel size of ~35 × 35 × 80 nm.
Across multiple cycles of staining, imaging, and antibody stripping, the same expanded tissue was repeatedly labeled,
enabling iterative immunostaining for dozens of molecular targets.

The dataset includes:
1) Light microscopy data of multiplexed brain tissue
2) Segmentations of cell morphology and protein expression in the tissue
3) Files for faster visualization of the data (e.g. [...]

## Categories & Sectors

- **Categories**: Automotive Data, Data Products, Healthcare & Life Sciences Data, Media & Entertainment Data, Public Sector Data, Resources Data, Telecommunications Data

## Marketplace Presence

- **Source Platforms**: aws_marketplace
- **Platform Count**: 1

## Intelligence Scores

- **Vendor Score**: 17.8
- **Market Presence**: 20.2
- **Integration**: 15
- **Business Maturity**: 7.9

## Links

- Vedex Profile: https://vedex.ai/vendor/gnomad-production-team-at-the-broad-institute-b104da
- Due Diligence: https://vedex.ai/due-diligence/gnomad-production-team-at-the-broad-institute-b104da